Latest News

Congratulations, Dr. EunCheon Lim!

Posted on May 04, 2016

EunCheon successfully defended his PhD thesis entitled 'A large-scale computational framework for comparative analyses in population genetics and metagenomics' read more

Congratulations, EunCheon!

Congratulations, Dr. Danelle Seymour!

Posted on April 29, 2016

Danelle successfully defended her PhD thesis entitled 'On the Genetics and Genomics of Arabidopsis thaliana and its Relatives’ and received the exceptional summa cum laude grade. read more

Congratulations, Danelle!

Growth inhibition by allelochemicals - don't need much

Posted on April 26, 2016

Allelochemicals of the phenoxazinone class act at physiologically relevant concentrations. read more

Venturelli, S., Petersen, S., Langenecker, T., Weigel, D., Lauer, U. and Becker, C.

Plants compete with their neighbors via the release of chemical compounds into the rhizosphere. These phytotoxins originate from a series of secondary metabolites and can be processed further by soil-living microorganisms before exerting their activity on the target plant. To determine the molecular mode of action and the physiological relevance of potential phytotoxins, it is important to simulate true-to-life conditions in laboratory experiments, for example by applying physiologically relevant concentrations. Here, we report on an improved experimental setting to study the function of allelochemicals of the benzoxazolinone class. By adjusting the solvent and the application of the chemicals, we reduced by more than twenty-fold the concentration that is necessary to induce growth defects in the model plant Arabidopsis thaliana.

Farewell to Jane

Posted on March 24, 2016

We’re saying goodbye to Jane and wish her all the best for her new adventures in agroecology in France! read more

Collaborative paper with Oliver Mathieu's group

Posted on March 23, 2016

Epigenome confrontation triggers immediate reprogramming of DNA methylation and transposon silencing in A. thaliana F1 epihybrids. read more

Rigal, M., Becker, C., Pélissier, T., Pogorelcnik, R., Devos, J., Ikeda, Z., Weigel, D., and Mathieu, O.

Genes and transposons can exist in variable DNA methylation states, with potentially differential transcription. How these epialleles emerge is poorly understood. Here, we show that crossing an Arabidopsis thaliana plant with a hypomethylated genome and a normally methylated WT individual results, already in the F1 generation, in widespread changes in DNA methylation and transcription patterns. Novel nonparental and heritable epialleles arise at many genic loci, including a locus that itself controls DNA methylation patterns, but with most of the changes affecting pericentromeric transposons. Although a subset of transposons show immediate resilencing, a large number display decreased DNA methylation, which is associated with de novo or enhanced transcriptional activation and can translate into transposon mobilization in the progeny. Our findings reveal that the combination of distinct epigenomes can be viewed as an epigenomic shock, which is characterized by a round of epigenetic variation creating novel patterns of gene and TE regulation.

Talia receives HFSP fellowship

Posted on March 18, 2016

Congratulations to Talia for receiving an HFSP post-doctoral fellowship!

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Upcoming Events

Jun
01

MiKo Talk Titia Sixma

June 1, 2016, 3 pm
MPH Lecture Hall

Title: "TBA"


Jun
02

Workshop: "New methods for old DNA"

June 2-3, 2016
at the Royal Belgian Institute of Natural Sciences, Brussel

Hernán speaking about "Ancient DNA and plant genomics"


Jun
08

MiKo Talk John Novembre